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We are thankful to L. Nunez-Pones, J. Moles, S. Taboada, J. Cristobo, A. Riesgo and M. Bas for their laboratory support. We are very grateful to Dr A. Cuni and Dr. K. Tilbrook, who kindly reviewed the manuscript for English grammar. In this work we used the extracts from previous projects (ECOQUIM projects), for this reason we want to thank W. Arntz, and the R/V Polarstern and the BIO-Hesperides crews. We would like to thank as well the Unidad de Tecnologia Marina (UTM) and the crew of Las Palmas vessel for all their logistic support. Special thanks are also given to the "Gabriel de Castilla BAE" crew for their help. This research was developed in the frame of the ACTIQUIM I and II projects (CGL2007-65453/ANT, CTM2010-17415/ANT) with the financial support of the Spanish Government. L. Sala-Comorera and C. Angulo are recipients of FPU and FPI grants from the Spanish Government, respectively (FPU12/00614, BES-2010-035521).

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Antimicrobial activity of Antarctic bryozoans: An ecological perspective with potential for clinical applications

Publicat a:Marine Environmental Research. 101 52-59 - 2014-10-01 101(), DOI: 10.1016/j.marenvres.2014.09.001

Autors: Figuerola, Blanca; Sala-Comorera, Laura; Angulo-Preckler, Carlos; Vazquez, Jennifer; Montes, M Jesus; Garcia-Aljaro, Cristina; Mercade, Elena; Blanch, Anicet R; Avila, Conxita

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The antimicrobial activity of Antarctic bryozoans and the ecological functions of the chemical compounds involved remain largely unknown. To determine the significant ecological and applied antimicrobial effects, 16 ether and 16 butanol extracts obtained from 13 different bryozoan species were tested against six Antarctic (including Psychrobacter luti, Shewanella livingstonensis and 4 new isolated strains) and two bacterial strains from culture collections (Escherichia coli and Bacillus cereus). Results from the bioassays reveal that all ether extracts exhibited antimicrobial activity against some bacteria. Only one butanol extract produced inhibition, indicating that antimicrobial compounds are mainly lipophilic. Ether extracts of the genus Camptoplites inhibited the majority of bacterial strains, thus indicating a broad-spectrum of antimicrobial activity. Moreover, most ether extracts presented activities against bacterial strains from culture collections, suggesting the potential use of these extracts as antimicrobial drugs against pathogenic bacteria. (C) 2014 Elsevier Ltd. All rights reserved.

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